A new weighted rough set framework based classification for Egyptian NeoNatal Jaundice

Prediction of diseases would help physicians to make informal decision regarding the type of treatment. Jaundice is the most common condition that requires medical attention in newborn babies. Although most newborns develop some degree of jaundice, a high level bilirubin puts a newborn at risk of bilirubin encephalopathy and kernicterus, which are rare but still occur in Egypt. This paper presents a new vailable online 16 December 2011 eywords: eighted rough set eonatal jaundice weighted rough set framework for early intervention and prevention of neurological dysfunction and kernicterus that are catastrophic sequels of neonatal jaundice. The obtained results illustrate that the weighted rough set can provide significantly more accurate and reliable predictive accuracy than well known algorithms such as weighted SVM and decision tree considering the fact that physicians do not t pro lass imbalance learning ule importance have any estimation abou . Introduction and motivation Neonatal jaundice, although a normal transitional phenomenon n most infants, can occasionally become more pronounced. Blood roup incompatibilities (e.g., Rh, ABO) may increase bilirubin roduction through increased hemolysis. Historically, Rh isoimmuization was an important cause of severe jaundice, often resulting n the development of kernicterus. Although this condition has ecome relatively rare in industrialized countries following the se of Rh prophylaxis in Rh-negative women, Rh isoimmunization emains common in developing countries [34]. About 60% of term abies, and 80% of preterm babies, develop jaundice in their first eek of life. 10% of breastfed babies are still jaundiced at 1 month of ge. Rapid differentiation between the majority of babies with jaunice who have no underlying disease (physiological jaundice) and hose with pathological causes is important to detect the underying disease and to prevent adverse sequelae such as bilirubin ncephalopathy and kernicterus [1]. The increased bilirubin cause the infant’s skin and whiteess of the eyes (sclera) to look yellow. Kernicterus, or bilirubin ncephalopathy, is a condition caused by bilirubin toxicity to the asal ganglia and various brainstem nuclei. In the acute phase, everely jaundiced infants become lethargic, hypotonic and suck oorly. If the hyperbilirubinemia is not treated, the infant becomes ∗ Corresponding author. Tel.: +2